A Contract
Science Company
Absolute
Science, Inc. is dedicated to helping you streamline your research efforts. We
offer a variety of contract services including, synthetic
chemistry, medicinal chemistry, combinatorial chemistry and assay development. Contact us or fill in the quote form and let us show you how we can help.
We have
experience in total synthesis and natural products chemistry. We can work on
milligram to 100's of grams quantities, and are dedicated to helping you with
all of your synthetic needs.
Scale up of Starting Materials or
Intermediates
Scale up of Scaffolds for CombiChem
Optimization of your Chemistries
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Our CSO,
Dr. S. T. Moe, has a proven track record of developing lead structures into
clinical candidates, sucessfully moving five separate lead compounds into the
clinic. His expertise and
intuition in medicinal chemistry provides our clients with a competitive
advantage in the drug development arena.
We are
capable of designing receptor agonists and antagonists as well as enzyme
inhibitors and substrates. We can help you generate your lead structures or
optimize the compounds you have. We will help develop the tools you need to
study your proprietary enzyme - from development of a fluorgenic substrate to
the synthesis of a standard inhibitor.
AMC, nitroanilides and other
fluorgenic substrates
Peptidyl aldehydes and
Halomethylketones
Vinylsulfones
Phosphonates
Peptidomimetics
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Absolute
Science can design and synthesize Combinatorial Libraries for your lead
identification. We have experience in both solution phase and solid phase
synthesis. We can develop libraries based upon your target or based upon a
known lead compound.
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We are
experienced with most of the major automatons and workstations, allowing as to
automate your assays for high throughput screening (HTS). We can also help in
the design and set-up of your database needs for data storage and data mining.
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For many
of your needs, we can provide you with a quotation from the comfort of your
desktop! For those materials which do not require a signed Confidentiality
Agreement, please fill in the form below and we will get back to you within 24
hours.
*: Most chemical drawing
software allow you to save your structures as SMILES strings. Simply "Cut
& Paste" the string into the box above.
For more complicated structures
or if you do not have access to your SMILES string please FAX us at
781.676.0010 or give us a call at 781.676.0010
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